Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9419588 | 0.86 | TTR (0.42) | RIPK1TTRBCL2BCL2L1SLC6A4 | |
| SCHEMBL11228892 | 0.82 | HRH1 (0.39) | RIPK1TTRBCL2BCL2L1SLC6A4 | |
| SCHEMBL28593839 | 0.79 | BCL2 (0.54) | BCL2BCL2L1HTR2AKMT2ACALM1 | |
| Fluoride SCHEMBL28569108 | 0.77 | BCL2 (0.52) | BCL2BCL2L1HTR2AKMT2ACALM1 | |
| SCHEMBL1204710 | 0.76 | CALM1 (0.44) | BCL2BCL2L1HTR2AHRH1CALM1 | |
| SCHEMBL28180000 | 0.76 | HRH1 (0.58) | RIPK1SLC6A4HTR2AHRH1SLC6A2 | |
| SCHEMBL9816698 | 0.76 | DPP4 (0.50) | RIPK1TTRSLC6A4HTR2AHRH1 | |
| Phosphine SCHEMBL28179254 | 0.74 | HRH1 (0.56) | RIPK1SLC6A4HTR2AHRH1SLC6A2 | |
| SCHEMBL20561451 | 0.71 | BCL2 (0.67) | BCL2BCL2L1KMT2ACALM1 | |
| SCHEMBL28009449 | 0.71 | BCL2 (0.45) | BCL2BCL2L1HTR2AKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4751258-A | BLEND OF POLYEPOXIDE, ETHYLENE OXIDE-PROPYLENE OXIDE COPOLYMER MODIFIED WITH AROMATIC ETHER, ETHYLENE OXIDE ALKYLPHENOL ADDUCT AND FATTY ESTER | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 1988-06-14 | — | — | US | disclosed |