Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10609926 | 0.82 | RIPK1 (0.41) | HRH1RIPK1DPP4TTRBCL2 | |
| SCHEMBL9419588 | 0.75 | TTR (0.42) | HRH1RIPK1DPP4TTRBCL2 | |
| SCHEMBL10628572 | 0.73 | HRH1 (0.37) | HRH1RIPK1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9816698 | 0.72 | DPP4 (0.50) | HRH1RIPK1DPP4TTRHTR2A | |
| SCHEMBL28180000 | 0.72 | HRH1 (0.58) | HRH1RIPK1CYP1A2CYP3A4CYP2C9 | |
| Phosphine SCHEMBL28179254 | 0.71 | HRH1 (0.56) | HRH1RIPK1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3970500 | 0.70 | BCL2 (0.41) | CYP3A4CYP2C19BCL2BCL2L1HTR2A | |
| SCHEMBL31539219 | 0.70 | MAOA (0.48) | HRH1CYP3A4SMN1; SMN2HTR2ASLC6A4 | |
| SCHEMBL9458270 | 0.69 | BCL2 (0.37) | CYP3A4BCL2BCL2L1HTR2A | |
| SCHEMBL679994 | 0.69 | CYP1A2 (0.52) | HRH1CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309294-A | OIL ADDITIVES | UOP INC. (US) | 1982-01-05 | — | — | US | disclosed |