Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | MAOA | P21397 | 4/20 | 0.69 |
| ▸ | ACHE | P22303 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ACSL1 | P33121 | 4/20 | 0.58 |
| ▸ | ACSL6 | Q9UKU0 | 3/20 | 0.58 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10611335 | 0.90 | NPC1 (0.82) | NPC1RAB9APOLBL3MBTL1MAOA | |
| SCHEMBL394209 | 0.82 | MAOA (1.00) | NPC1RAB9APOLBL3MBTL1MAOA | |
| SCHEMBL9413588 | 0.81 | NPC1 (0.68) | NPC1RAB9APOLBL3MBTL1MAOA | |
| SCHEMBL30536437 | 0.79 | MAOA (0.72) | NPC1RAB9APOLBL3MBTL1MAOA | |
| SCHEMBL20594364 | 0.79 | MAOA (0.72) | NPC1RAB9APOLBL3MBTL1MAOA | |
| Ethylene SCHEMBL18528476 | 0.79 | MAOA (0.94) | NPC1RAB9APOLBL3MBTL1MAOA | |
| Dibenzofuran SCHEMBL11430526 | 0.79 | NPC1 (0.65) | NPC1RAB9APOLBL3MBTL1MAOA | |
| Xanthone SCHEMBL28434710 | 0.78 | MAOA (0.95) | NPC1RAB9APOLBL3MBTL1MAOA | |
| SCHEMBL30130333 | 0.78 | MAOA (0.70) | NPC1RAB9APOLBL3MBTL1MAOA | |
| SCHEMBL392389 | 0.78 | MAOA (0.70) | NPC1RAB9APOLBL3MBTL1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4767837-A | Method for preparing poly(aryl ether ketones) | RAYCHEM CORPORATION (US) | 1988-08-30 | — | — | US | disclosed |