SCHEMBL394209

SCHEMBL394209

COc1ccc2oc3ccccc3c(=O)c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 1.00
NPC1 O15118 5/20 0.83
KDM4E B2RXH2 5/20 0.83
RAB9A P51151 4/20 0.83
ALDH1A1 P00352 4/20 0.83
HPGD P15428 4/20 0.83
MAPT P10636 3/20 0.83
SMN1; SMN2 Q16637 3/20 0.83
CASP3 P42574 1/20 0.83
SENP8 Q96LD8 1/20 0.83
SENP7 Q9BQF6 1/20 0.83
SENP6 Q9GZR1 1/20 0.83
POLB P06746 1/20 0.69
L3MBTL1 Q9Y468 1/20 0.69
MEN1 O00255 1/20 0.69
KMT2A Q03164 1/20 0.69
HSD17B10 Q99714 3/20 0.65
CYP3A4 P08684 2/20 0.65
TSHR P16473 2/20 0.65
CYP2D6 P10635 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL18528476 0.97 MAOA (0.94) MAOANPC1KDM4ERAB9AALDH1A1
Ethylene Glycol SCHEMBL18525379 0.93 MAOA (0.86) MAOANPC1KDM4ERAB9AALDH1A1
SCHEMBL1567209 0.93 MAOA (0.86) MAOANPC1KDM4ERAB9AALDH1A1
SCHEMBL2161251 0.91 ALDH1A1 (1.00) MAOANPC1KDM4ERAB9AALDH1A1
SCHEMBL29619913 0.91 ALDH1A1 (1.00) MAOANPC1KDM4ERAB9AALDH1A1
SCHEMBL789950 0.90 MAOA (1.00) MAOANPC1KDM4ERAB9AALDH1A1
SCHEMBL29958722 0.90 MAOA (1.00) MAOANPC1KDM4ERAB9AALDH1A1
SCHEMBL7331388 0.88 KDM4E (0.86) MAOANPC1KDM4ERAB9AALDH1A1
SCHEMBL20317207 0.87 NPC1 (0.78) MAOANPC1KDM4ERAB9AALDH1A1
SCHEMBL20346628 0.86 MAOA (0.76) MAOANPC1KDM4ERAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 429 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3808348-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML) Biogen MA Inc. (US) 2021-04-21 EP claimed
US-20130245070-A1 COMPOUNDS FOR ENHANCING ARGINASE ACTIVITY AND METHODS OF USING SAME THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2013-09-19 US claimed
US-20130183289-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML) BIOGEN IDEC MA INC (US) 2013-07-18 US claimed
EP-2200611-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML) Biogen Idec MA, Inc. (US) 2010-06-30 EP claimed
US-20090253782-A1 Compounds for Enhancing Arginase Activity and Methods of USe Thereof CORNELL RESEARCH FOUNDATION, INC. 2009-10-08 US claimed
WO-2009038684-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY (PML) BIOGEN IDEC MA INC. (US) 2009-03-26 WO claimed
WO-2008011083-A2 COMPOUNDS FOR ENHANCING ARGINASE ACTIVITY AND METHODS OF USE THEREOF CORNELL RESEARCH FOUNDATION, INC. (US) 2008-01-24 WO claimed
EP-0368327-B1 Light-sensitive composition FUJI PHOTO FILM CO LTD (JP) 1995-02-15 EP claimed
US-5202221-A Photocrosslinkable copolymer having maleimido side chain, cyanine dye sensitizer FUJI PHOTO FILM CO., LTD. (JP) 1993-04-13 US claimed
US-5110709-A Photoresists of excellent image resolution FUJI PHOTO FILM CO., LTD. (JP) 1992-05-05 US claimed
US-5002853-A Polymeric Sulfonyloxy-Amides and Iides FUJI PHOTO FILM CO., LTD. (JP) 1991-03-26 US claimed
EP-0368327-A2 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1990-05-16 EP claimed
EP-0363198-A2 Positive working photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1990-04-11 EP claimed
US-4258121-A SULFONYLOXY N-SUBSTITUTED IMIDES AS PHOTOINITIATORS FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 US claimed
CN-119775478-A Dispersing resin, coloring composition for color filter, and solid-state imaging element 爱天思株式会社 2025-04-08 CN disclosed
CN-118099173-A Solid-state imaging element, method for manufacturing solid-state imaging element, and electronic device 爱天思株式会社 2024-05-28 CN disclosed
CN-111295379-B Free radical photoinitiators and their use in silicone compositions 埃肯有机硅法国简易股份公司 2023-08-22 CN disclosed
US-4258121-A SULFONYLOXY N-SUBSTITUTED IMIDES AS PHOTOINITIATORS FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 US disclosed
EP-0005380-A2 Phototropic photosensitive compositions containing a fluoran colorformer Dynachem Corporation (US) 1979-11-14 EP disclosed
EP-0005379-A2 Photosensitive compositions containing carbonylic halides as activators Dynachem Corporation (US) 1979-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130245070-A1 COMPOUNDS FOR ENHANCING ARGINASE ACTIVITY AND METHODS OF USING SAME ARG2, ARG1, OTC MAOA 197/4885NPC1 1418/4885KDM4E 1426/4885
US-20090253782-A1 Compounds for Enhancing Arginase Activity and Methods of USe Thereof ARG2, ARG1, OTC MAOA 163/4885NPC1 1483/4885KDM4E 1521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.