Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | TTPA | P49638 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.36 |
| ▸ | AKT1 | P31749 | 3/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | PHLPP1 | O60346 | 1/20 | 0.35 |
| ▸ | ILK | Q13418 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20819447 | 0.75 | ALOX5 (0.41) | LMNAMAPTMEN1KMT2AGSTP1 | |
| SCHEMBL20819448 | 0.75 | ALOX5 (0.41) | LMNAMAPTMEN1KMT2AGSTP1 | |
| SCHEMBL8843243 | 0.72 | ALOX5 (0.37) | LMNAMAPTMEN1KMT2AGSTP1 | |
| SCHEMBL20822166 | 0.70 | AKT1 (0.36) | LMNAMAPTMEN1KMT2AGSTP1 | |
| SCHEMBL20749446 | 0.70 | LMNA (0.68) | PSEN1LMNAMAPTMEN1KMT2A | |
| SCHEMBL19335852 | 0.70 | LMNA (0.68) | PSEN1LMNAMAPTMEN1KMT2A | |
| SCHEMBL5460830 | 0.68 | PTGS1 (0.36) | PSEN1ALOX5 | |
| SCHEMBL28010015 | 0.64 | MAPT (0.65) | PSEN1LMNAMAPTMEN1KMT2A | |
| SCHEMBL28010631 | 0.64 | MAPT (0.65) | PSEN1LMNAMAPTMEN1KMT2A | |
| SCHEMBL21646267 | 0.64 | PTGS1 (0.33) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0191463-A3 | STABILIZERS | BASF Aktiengesellschaft (DE) | 1988-03-02 | — | — | EP | disclosed |
| EP-0191463-A2 | Stabilizers | BASF Aktiengesellschaft (DE) | 1986-08-20 | — | — | EP | disclosed |