Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.63 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 4/20 | 0.48 |
| ▸ | CES1 | P23141 | 4/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL9505237 | 0.97 | SLC22A1 (0.60) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL27860993 | 0.97 | SLC22A1 (0.60) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL9505231 | 0.95 | SLC22A1 (0.57) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL16343940 | 0.95 | SLC22A1 (0.63) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL17768456 | 0.93 | SLC22A1 (0.55) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Oxalic Acid SCHEMBL1052717 | 0.92 | SLC22A1 (0.65) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL18109154 | 0.92 | SLC22A1 (0.60) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL16093909 | 0.92 | SLC22A1 (0.60) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL3488443 | 0.92 | SLC22A1 (0.60) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL3488441 | 0.92 | SLC22A1 (0.60) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115785425-A | Carbon dioxide-based polycarbonate-polyether block polyol and preparation method thereof | 佛山市中天融新材料科技有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-115073458-A | Preparation method of avibactam sodium | 山东致泰医药技术有限公司 | 2022-09-20 | — | — | CN | claimed |
| US-8389178-B2 | Electrochemical energy storage device based on carbon dioxide as electroactive species | U.S. DEPARTMENT OF ENERGY (US) | 2013-03-05 | — | — | US | claimed |
| EP-2011798-B1 | Preparation of platinum (II) complexes | PLATCO TECHNOLOGIES PROPRIETARY LTD (ZA) | 2011-06-29 | — | — | EP | claimed |
| US-7956208-B2 | Preparation of platinum (II) complexes | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2011-06-07 | — | — | US | claimed |
| US-7888523-B2 | Preparation of platinum(II) complexes | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2011-02-15 | — | — | US | claimed |
| US-20100330435-A1 | ELECTROCHEMICAL ENERGY STORAGE DEVICE BASED ON CARBON DIOXIDE AS ELECTROACTIVE SPECIES | U.S. DEPT. OF ENERGY (US) | 2010-12-30 | — | — | US | claimed |
| US-20090299085-A1 | PREPARATION OF PLATINUM(II) COMPLEXES | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2009-12-03 | — | — | US | claimed |
| US-20090281319-A1 | PREPARATION OF PLATINUM (II) COMPLEXES | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2009-11-12 | — | — | US | claimed |
| US-7589225-B2 | Preparation of platinum(II) complexes | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2009-09-15 | — | — | US | claimed |
| EP-1979369-A1 | PREPARATION OF PLATINUM (LL) COMPLEXES | Platco Technologies (Proprietary) Limited (ZA) | 2008-10-15 | — | — | EP | claimed |
| US-20080064895-A1 | Preparation of Platinum(II) Complexes | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2008-03-13 | — | — | US | claimed |
| WO-2007085957-A1 | PREPARATION OF PLATINUM (LL) COMPLEXES | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2007-08-02 | — | — | WO | claimed |
| EP-1789427-A1 | PREPARATION OF PLATINUM(II) COMPLEXES | Platco Technologies (Proprietary) Limited (ZA) | 2007-05-30 | — | — | EP | claimed |
| WO-2006024897-A1 | PREPARATION OF PLATINUM(II) COMPLEXES | PLATCO TECHNOLOGIES (PROPRIETARY) LIMITED (ZA) | 2006-03-09 | — | — | WO | claimed |
| EP-1142049-B1 | HYDROFLUORIC ACID SCAVENGER | DANIONICS AS (DK) | 2002-09-18 | — | — | EP | claimed |
| WO-2000042672-A9 | HYDROFLUORIC ACID SCAVENGER | DANIONICS AS (DK) | 2001-11-15 | — | — | WO | claimed |
| EP-1142049-A2 | HYDROFLUORIC ACID SCAVENGER | DANIONICS A/S (DK) | 2001-10-10 | — | — | EP | claimed |
| WO-2000042672-A2 | HYDROFLUORIC ACID SCAVENGER | DANIONICS A/S (DK) | 2000-07-20 | — | — | WO | claimed |
| EP-0398615-B1 | PROCESS FOR SOLUBILIZING POLYANIONIC BACTERIAL POLYSACCHARIDES IN APROTIC SOLVENTS | MERCK & CO. INC. (US) | 1993-07-14 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090299085-A1 | PREPARATION OF PLATINUM(II) COMPLEXES | SLCO4C1, OTC, SLC10A6 | SLC22A1 283/4885SLC22A2 261/4885ALDH1A1 3900/4885 |
| US-20080064895-A1 | Preparation of Platinum(II) Complexes | SLCO4C1, SLC10A6, OTC | SLC22A1 272/4885SLC22A2 254/4885ALDH1A1 3885/4885 |
| US-20090281319-A1 | PREPARATION OF PLATINUM (II) COMPLEXES | OAT, OTC, POLR2E | SLC22A1 857/4885SLC22A2 702/4885ALDH1A1 1641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.