Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | NAMPT | P43490 | 1/20 | 0.61 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 2/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29388820 | 0.83 | TSHR (0.67) | TSHRHSD17B10NAMPTPRMT1CA12 | |
| SCHEMBL20389159 | 0.82 | ALDH1A1 (0.60) | TSHRHSD17B10NAMPTMAPTLMNA | |
| SCHEMBL14384688 | 0.82 | LMNA (0.60) | HSD17B10NAMPTMAPTLMNAMEN1 | |
| SCHEMBL28095629 | 0.79 | TSHR (0.57) | TSHRHSD17B10NAMPTCA12CA1 | |
| SCHEMBL19377380 | 0.78 | NAMPT (0.76) | NAMPTCA12CA1CA2CA9 | |
| Benzylsulfonylbenzene SCHEMBL780337 | 0.78 | TSHR (0.68) | TSHRHSD17B10CA1CA2CA9 | |
| SCHEMBL11827401 | 0.77 | TSHR (1.00) | TSHRHSD17B10CA12CA1CA2 | |
| SCHEMBL20379729 | 0.77 | NAMPT (1.00) | NAMPTHTT | |
| SCHEMBL2921402 | 0.77 | TSHR (0.68) | TSHRHSD17B10NAMPTCA1CA2 | |
| SCHEMBL257997 | 0.77 | MAPT (0.64) | TSHRHSD17B10CA12CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132230-B1 | PROCESS FOR THE PREPARATION OF SULFONYL UREA | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | disclosed |
| EP-0132230-A2 | Process for the preparation of sulfonyl urea | CIBA-GEIGY AG (CH) | 1985-01-23 | — | — | EP | disclosed |