Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10617418 | 0.86 | ALDH1A1 (0.49) | HPGDKDM4EALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL10617208 | 0.82 | ALDH1A1 (0.44) | HPGDKDM4EALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL10620227 | 0.78 | KDM4E (0.52) | HPGDKDM4EALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL10617810 | 0.78 | TARBP2 (0.45) | HPGDKDM4EALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL10620352 | 0.77 | KDM4E (0.45) | HPGDKDM4EALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL10617874 | 0.76 | GAA (0.49) | HPGDKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL10617220 | 0.74 | KDM4E (0.42) | HPGDKDM4EALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL31126023 | 0.71 | ALDH1A1 (0.48) | HPGDKDM4EALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL8569614 | 0.71 | ALDH1A1 (0.57) | HPGDKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL10617234 | 0.71 | ALDH1A1 (0.38) | HPGDKDM4EALDH1A1ATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285267-A2 | Pyridine derivatives for treatment and prevention of liver damage, and their preparation | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-10-05 | — | — | EP | disclosed |