Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10617418 | 0.79 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDATMMAPT | |
| SCHEMBL10620225 | 0.79 | KDM4E (0.49) | KDM4EALDH1A1HPGDATMMAPT | |
| SCHEMBL10619132 | 0.78 | HPGD (0.48) | KDM4EALDH1A1HPGDATMMAPT | |
| SCHEMBL10620352 | 0.78 | KDM4E (0.45) | KDM4EALDH1A1HPGDATMMAPT | |
| SCHEMBL10617810 | 0.76 | TARBP2 (0.45) | KDM4EALDH1A1HPGDATMGAA | |
| SCHEMBL8576064 | 0.76 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDATMMAPT | |
| SCHEMBL10617926 | 0.75 | KDM4E (0.65) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL14361837 | 0.75 | MAPT (0.54) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL10617220 | 0.75 | KDM4E (0.42) | KDM4EALDH1A1HPGDATMMAPT | |
| SCHEMBL2954102 | 0.75 | KMT2A (0.48) | KDM4EALDH1A1HPGDATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285267-A2 | Pyridine derivatives for treatment and prevention of liver damage, and their preparation | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-10-05 | — | — | EP | disclosed |