Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546110 | 0.84 | — | — | |
| SCHEMBL9546174 | 0.83 | — | — | |
| SCHEMBL30183086 | 0.78 | PTGER3 (0.46) | PPARGALDH1A1LMNA | |
| SCHEMBL9546461 | 0.78 | TRPA1 (0.36) | PPARGALDH1A1LMNA | |
| SCHEMBL10619325 | 0.75 | NFKB1 (0.37) | PPARGPRKCA | |
| SCHEMBL10619328 | 0.75 | NFKB1 (0.37) | PPARGALDH1A1PRKCA | |
| SCHEMBL10603475 | 0.73 | NFKB1 (0.49) | PPARGALDH1A1LMNA | |
| SCHEMBL10772968 | 0.73 | NFKB1 (0.49) | PPARGALDH1A1LMNA | |
| SCHEMBL10603470 | 0.73 | NFKB1 (0.49) | PPARGALDH1A1LMNA | |
| SCHEMBL10772965 | 0.73 | NFKB1 (0.49) | PPARGALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766147-A | ANTITUMOR AGENTS | TEIJIN LIMITED (JP) | 1988-08-23 | — | — | US | disclosed |
| EP-0106576-B1 | NOVEL 5-MEMBERED CYCLIC COMPOUNDS, PROCESS FOR THE PRODUCTION THEREOF, AND PHARMACEUTICAL USE THEREOF | TEIJIN LIMITED (JP) | 1988-03-09 | — | — | EP | disclosed |