Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11118818 | 0.85 | TRPA1 (0.36) | TRPA1NR4A2MEN1ALDH1A1LMNA | |
| SCHEMBL9546109 | 0.83 | PPARG (0.30) | PPARG | |
| SCHEMBL9546383 | 0.82 | PPARG (0.31) | PPARGPPARA | |
| SCHEMBL9546211 | 0.80 | PPARG (0.35) | PPARGPPARA | |
| SCHEMBL10619366 | 0.78 | TRPA1 (0.59) | TRPA1NR4A2PPARGMEN1ALDH1A1 | |
| SCHEMBL10619374 | 0.78 | TRPA1 (0.59) | TRPA1NR4A2PPARGMEN1ALDH1A1 | |
| SCHEMBL9546442 | 0.76 | PTGER2 (0.37) | TRPA1NR4A2PPARGMEN1ALDH1A1 | |
| SCHEMBL9546451 | 0.73 | TRPA1 (0.45) | TRPA1NR4A2PPARGMEN1ALDH1A1 | |
| SCHEMBL10620216 | 0.72 | PTGIR (0.33) | PPARGPPARA | |
| SCHEMBL9546110 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338796-B1 | 2-SUBSTITUTED-2-CYCLOPENTENONES | TEIJIN LIMITED (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5116869-A | Antitumor Agents, Bone Formation Accelerator | TEIJIN LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0338796-A2 | 2-Substituted-2-cyclopentenones | TEIJIN LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |
| US-4766147-A | ANTITUMOR AGENTS | TEIJIN LIMITED (JP) | 1988-08-23 | — | — | US | disclosed |
| EP-0106576-B1 | NOVEL 5-MEMBERED CYCLIC COMPOUNDS, PROCESS FOR THE PRODUCTION THEREOF, AND PHARMACEUTICAL USE THEREOF | TEIJIN LIMITED (JP) | 1988-03-09 | — | — | EP | disclosed |