SCHEMBL10619644

SCHEMBL10619644

COCCCC[n+]1ccc(-c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
TP53 P04637 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
MAPT P10636 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
KMT2A Q03164 1/20 0.50
KDM4E B2RXH2 1/20 0.48
NPC1 O15118 1/20 0.48
LMNA P02545 1/20 0.48
HTT P42858 1/20 0.48
RAB9A P51151 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
SLC22A2 O15244 1/20 0.42
SLC22A1 O15245 1/20 0.42
SLC22A3 O75751 1/20 0.42
SLC6A4 P31645 1/20 0.42
CHRNA7 P36544 4/20 0.41
CHRNA10 Q9GZZ6 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15870654 0.82 BCHE (0.61) BCHEACHE
SCHEMBL17852176 0.80 MEN1 (0.44) MEN1TP53CYP1A2CYP2D6MAPT
Water SCHEMBL30259683 0.80 MEN1 (0.61) MEN1TP53CYP1A2CYP2D6MAPT
SCHEMBL256682 0.79 KMT2A (0.80) MEN1TP53CYP1A2CYP2D6MAPT
SCHEMBL15870653 0.77 BCHE (0.73) BCHEACHE
Biphenyl SCHEMBL27552897 0.76 LTA4H (0.50) TP53LMNA
SCHEMBL257336 0.76 KMT2A (0.69) MEN1TP53CYP1A2CYP2D6MAPT
SCHEMBL18569973 0.76 BCHE (0.56) BCHEACHE
Bromide SCHEMBL14656035 0.75 KMT2A (0.67) MEN1TP53CYP1A2CYP2D6MAPT
Hydrochloric Acid SCHEMBL6115198 0.74 BCHE (0.54) MEN1MAPTKMT2ASMN1; SMN2BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63044564-A None JP disclosed
JP-S6344564-A NOVEL TCNQ COMPLEX WAKO PURE CHEM IND LTD 1988-02-25 JP disclosed