Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.73 |
| ▸ | ACACB | O00763 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10618997 | 0.90 | ALOX5 (0.73) | ALOX5ACACB | |
| SCHEMBL9473341 | 0.89 | ALOX5 (0.75) | ALOX5ACACB | |
| SCHEMBL9668706 | 0.87 | ALOX5 (0.62) | ALOX5ACACBLMNAL3MBTL1 | |
| SCHEMBL7713248 | 0.85 | ALOX5 (0.78) | ALOX5 | |
| SCHEMBL8933773 | 0.84 | ALOX5 (1.00) | ALOX5 | |
| Ammonia Solution, Strong SCHEMBL9473339 | 0.83 | ALOX5 (0.97) | ALOX5 | |
| SCHEMBL9475019 | 0.83 | ALOX5 (0.97) | ALOX5 | |
| SCHEMBL9474724 | 0.83 | ALOX5 (0.97) | ALOX5 | |
| SCHEMBL9476192 | 0.83 | ALOX5 (0.74) | ALOX5 | |
| SCHEMBL10693843 | 0.80 | ALOX5 (1.00) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292699-A2 | Urea based lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1988-11-30 | — | — | EP | disclosed |