Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.62 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.57 |
| ▸ | ACACB | O00763 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10619656 | 0.87 | ALOX5 (0.73) | ALOX5ACACBLMNAL3MBTL1 | |
| SCHEMBL10618997 | 0.80 | ALOX5 (0.73) | ALOX5NPY5RACACBLTA4H | |
| SCHEMBL9473341 | 0.79 | ALOX5 (0.75) | ALOX5NPY5RACACBLTA4H | |
| SCHEMBL6739031 | 0.78 | ALOX5 (0.51) | ALOX5NPY5RACACBMAOBLTA4H | |
| SCHEMBL9476192 | 0.78 | ALOX5 (0.74) | ALOX5MAOB | |
| SCHEMBL7713248 | 0.77 | ALOX5 (0.78) | ALOX5 | |
| SCHEMBL9686116 | 0.77 | ACACB (0.67) | ALOX5NPY5RACACBMAOBLTA4H | |
| SCHEMBL8933773 | 0.76 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9685836 | 0.76 | ACACB (0.66) | ALOX5ACACBLTA4H | |
| SCHEMBL9474895 | 0.76 | ALOX5 (0.71) | ALOX5LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456760-A4 | LIPOXYGENASE INHIBITING COMPOUNDS | — | 1992-01-08 | — | — | EP | claimed |
| EP-0456760-A1 | LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1991-11-21 | — | — | EP | claimed |