Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ESRRA | P11474 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | BRD4 | O60885 | 3/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11326749 | 0.99 | TDP1 (0.59) | TDP1ESRRAALDH1A1MAPTBRD4 | |
| SCHEMBL3728922 | 0.88 | MAPT (0.51) | TDP1ESRRAALDH1A1MAPTBRD4 | |
| SCHEMBL28430906 | 0.88 | TDP1 (0.71) | TDP1ESRRAALDH1A1MAPTBRD4 | |
| SCHEMBL11325646 | 0.84 | MAPT (0.55) | ESRRAALDH1A1MAPTBRD4MTNR1A | |
| SCHEMBL6285132 | 0.82 | ESRRA (0.69) | ESRRAALDH1A1RORC | |
| SCHEMBL3728925 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPTMTNR1AMTNR1BCYP1A2 | |
| SCHEMBL14384694 | 0.82 | TTR (0.60) | ESRRAALDH1A1MAPTBRD4MTNR1A | |
| SCHEMBL10612285 | 0.82 | TDP1 (0.54) | TDP1ESRRAALDH1A1MAPTMTNR1A | |
| SCHEMBL15067981 | 0.82 | STK39 (0.58) | ESRRAALDH1A1MAPTBRD4MTNR1A | |
| SCHEMBL8590316 | 0.80 | TDP1 (0.66) | TDP1ALDH1A1MAPTRORCHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0165564-B1 | PROCESS FOR THE PREPARATION OF 4-ACYLAMINO-2-ALKYLAMINOPHENYL ETHERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-05-25 | — | — | EP | disclosed |
| EP-0165564-A2 | Process for the preparation of 4-acylamino-2-alkylaminophenyl ethers | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-12-27 | — | — | EP | disclosed |
| US-4248794-A | ACYLATION OF DIAMINOPHENYL ETHER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-02-03 | — | — | US | disclosed |