Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ESRRA | P11474 | 2/20 | 0.53 |
| ▸ | BRD4 | O60885 | 2/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PYGL | P06737 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10616610 | 0.88 | MAPT (0.53) | MAPTLMNAALDH1A1HTTESRRA | |
| SCHEMBL11546464 | 0.85 | ALDH1A1 (0.53) | MAPTALDH1A1HTTESRRAMTNR1A | |
| SCHEMBL10416922 | 0.85 | NPSR1 (0.50) | MAPTLMNAHTTBRD4CYP1A2 | |
| SCHEMBL1638973 | 0.84 | L3MBTL1 (0.57) | MAPTLMNAHTTCYP1A2CYP3A4 | |
| SCHEMBL8787198 | 0.84 | L3MBTL1 (0.64) | MAPTLMNAALDH1A1HTTCYP1A2 | |
| SCHEMBL10620277 | 0.84 | TDP1 (0.61) | MAPTLMNAALDH1A1ESRRABRD4 | |
| SCHEMBL6285132 | 0.84 | ESRRA (0.69) | ALDH1A1ESRRARORCGAA | |
| SCHEMBL14384694 | 0.84 | TTR (0.60) | MAPTLMNAALDH1A1HTTESRRA | |
| SCHEMBL15067981 | 0.84 | STK39 (0.58) | MAPTLMNAALDH1A1ESRRABRD4 | |
| Hydrochloric Acid SCHEMBL11330417 | 0.82 | NPSR1 (0.48) | MAPTLMNAALDH1A1HTTBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4248794-A | ACYLATION OF DIAMINOPHENYL ETHER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-02-03 | — | — | US | disclosed |