Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.60 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARD | Q03181 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stearic Acid SCHEMBL10430551 | 0.86 | GPR84 (0.55) | ALDH1A1ASAH1ACER2GPR84PPARG | |
| Hexanoate SCHEMBL28233555 | 0.84 | AKR1B1 (0.53) | ALDH1A1ASAH1ACER2GPR84PPARG | |
| Stearic Acid SCHEMBL2369752 | 0.83 | ALDH1A1 (0.69) | ALDH1A1ASAH1ACER2ADRA2CLMNA | |
| Decanoic Acid SCHEMBL2370923 | 0.83 | ALDH1A1 (0.69) | ALDH1A1ASAH1ACER2ADRA2CLMNA | |
| Stearic Acid SCHEMBL2369756 | 0.83 | ALDH1A1 (0.69) | ALDH1A1ASAH1ACER2ADRA2CLMNA | |
| Decanoic Acid SCHEMBL2370921 | 0.83 | ALDH1A1 (0.69) | ALDH1A1ASAH1ACER2ADRA2CLMNA | |
| Octanoic Acid SCHEMBL28100072 | 0.83 | GPR84 (0.59) | ALDH1A1ASAH1ACER2GPR84PPARG | |
| Diphenylmethanol SCHEMBL27813920 | 0.83 | GPR84 (0.59) | ALDH1A1ASAH1ACER2GPR84PPARG | |
| (1S,2R)-Phenylpropanolamine SCHEMBL28117235 | 0.81 | ASAH1 (0.59) | ALDH1A1ASAH1ACER2ADRA2AADRA2C | |
| Isopropylbenzene SCHEMBL27527935 | 0.81 | AKR1B1 (0.57) | ALDH1A1ASAH1ACER2GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1988002253-A1 | COATING MEMBRANE AND COMPOSITIONS PREPARED THEREFROM | VALDUCCI ROBERTO (IT) | 1988-04-07 | — | — | WO | claimed |