Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721931 | 0.93 | POLB (0.40) | POLBALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL28386489 | 0.87 | POLB (0.34) | POLB | |
| SCHEMBL7795745 | 0.87 | POLB (0.50) | POLBALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL9835185 | 0.80 | POLB (0.44) | POLBALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL31589510 | 0.72 | POLB (0.41) | POLBALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL23934909 | 0.71 | MAPT (0.40) | POLBALDH1A1CYP3A4TSHR | |
| SCHEMBL3774780 | 0.69 | ALDH1A1 (0.43) | POLBALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL541137 | 0.69 | POLB (0.48) | POLBALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL1162419 | 0.68 | CYP3A4 (0.34) | POLBTP53CYP3A4TSHRTDP1 | |
| SCHEMBL16022232 | 0.68 | ALDH1A1 (0.52) | POLBALDH1A1TP53CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745223-A | CHAIN EXTENDERS FOR POLYUREAS AND POLYURETHANES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1988-05-17 | — | — | US | disclosed |
| EP-0177916-A1 | Mono-tertiary-alkylated toluenediamine and derivatives | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-04-16 | — | — | EP | disclosed |