Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Acetate SCHEMBL28008204 | 0.91 | ALDH1A1 (0.52) | TSHRTHRBMGAMGAASI | |
| Isopropyl Alcohol SCHEMBL11332211 | 0.88 | TSHR (0.59) | TSHRTHRBMGAMGAASI | |
| Urethane SCHEMBL4858633 | 0.87 | ALOX15 (0.52) | TSHRTHRBMGAMGAASI | |
| Ether SCHEMBL28937460 | 0.86 | THRB (0.50) | TSHRTHRBMGAMGAASI | |
| SCHEMBL11295643 | 0.86 | TSHR (0.53) | TSHRTHRBMGAMGAASI | |
| Alcohol SCHEMBL27759500 | 0.86 | TSHR (0.47) | TSHRTHRBMGAMGAASI | |
| SCHEMBL10762910 | 0.85 | — | — | |
| SCHEMBL27553112 | 0.85 | TSHR (0.48) | TSHRTHRBALDH1A1HSD17B10 | |
| SCHEMBL20364 | 0.85 | — | — | |
| SCHEMBL11125870 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4770665-A | IN SITU FORMATION OF TISSUE BONDED ACRYLIC POLYMER | AMERICAN HOSPITAL SUPPLY CORPORATION (US) | 1988-09-13 | — | — | US | disclosed |