Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | GAPDH | P04406 | 2/20 | 0.42 |
| ▸ | HRAS | P01112 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | F11 | P03951 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10620684 | 0.86 | ALDH1A1 (0.48) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL10624065 | 0.80 | LMNA (0.47) | CA1CA2CA9ALDH1A1GALR3 | |
| SCHEMBL10706978 | 0.75 | MEN1 (0.56) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL10620690 | 0.74 | MEN1 (0.54) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL5746383 | 0.74 | MEN1 (0.54) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL24941146 | 0.73 | USP2 (0.52) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL10865013 | 0.73 | USP2 (0.52) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL10864836 | 0.73 | USP2 (0.52) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL7148935 | 0.73 | USP2 (0.52) | MEN1USP2POLBKMT2ACA1 | |
| SCHEMBL7213369 | 0.73 | USP2 (0.52) | MEN1USP2POLBKMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4728729-A | ANTITUMOR, IMMUNOSUPPRESSANT | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1988-03-01 | — | — | US | claimed |
| US-4728729-A | ANTITUMOR, IMMUNOSUPPRESSANT | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1988-03-01 | — | — | US | disclosed |