Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | PNP | P00491 | 2/20 | 0.37 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10620698 | 0.86 | MEN1 (0.53) | ALDH1A1HTTMEN1USP2POLB | |
| SCHEMBL10623379 | 0.83 | LMNA (0.33) | ALDH1A1CA1CA2CA9LMNA | |
| SCHEMBL6273372 | 0.73 | ALDH1A1 (0.53) | ALDH1A1HTTPOLBKMT2ALMNA | |
| SCHEMBL6273371 | 0.73 | ALDH1A1 (0.53) | ALDH1A1HTTPOLBKMT2ALMNA | |
| SCHEMBL10708190 | 0.73 | ALDH1A1 (0.49) | ALDH1A1HTTMEN1USP2POLB | |
| SCHEMBL10620674 | 0.73 | ALDH1A1 (0.53) | ALDH1A1HTTABCB1LMNAGSK3A | |
| SCHEMBL7830323 | 0.72 | ALDH1A1 (0.48) | ALDH1A1HTTPOLBKMT2A | |
| SCHEMBL10708875 | 0.72 | ALDH1A1 (0.52) | ALDH1A1HTTNT5EP2RY6P2RY14 | |
| SCHEMBL11175487 | 0.69 | LGALS9 (0.54) | ALDH1A1HTTPOLB | |
| SCHEMBL11175481 | 0.69 | LGALS9 (0.54) | ALDH1A1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155164-B1 | NOVEL CYANOIMIDAZOLE NUCLEOSIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-11-17 | — | — | EP | claimed |
| US-4728729-A | ANTITUMOR, IMMUNOSUPPRESSANT | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1988-03-01 | — | — | US | claimed |
| US-4728729-A | ANTITUMOR, IMMUNOSUPPRESSANT | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1988-03-01 | — | — | US | disclosed |