Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.44 |
| ▸ | TNNI3K | Q59H18 | 4/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FUT8 | Q9BYC5 | 1/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11131894 | 0.83 | CDK2 (0.37) | TNNI3KLRRK2PTK2 | |
| SCHEMBL11134269 | 0.83 | PTK2 (0.43) | TNNI3KLRRK2PTK2EPHB4 | |
| SCHEMBL8636120 | 0.73 | CASR (0.47) | CASRLMNAALDH1A1MAPTCASP6 | |
| SCHEMBL11135444 | 0.72 | PTK2 (0.43) | TNNI3KLRRK2PTK2EPHB4 | |
| SCHEMBL14606512 | 0.72 | CASR (0.49) | CASRNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL18902955 | 0.70 | TNNI3K (0.40) | TNNI3KLRRK2FUT8ALDH1A1CASP6 | |
| SCHEMBL11532165 | 0.69 | LRRK2 (0.41) | TNNI3KLRRK2NPC1RAB9APTK2 | |
| SCHEMBL9422589 | 0.69 | LRRK2 (0.45) | LRRK2ALDH1A1MAPTCASP6KMT2A | |
| SCHEMBL18902953 | 0.67 | FUT8 (0.38) | TNNI3KFUT8ALDH1A1CASP6KMT2A | |
| SCHEMBL10621173 | 0.67 | LMNA (0.41) | TNNI3KLRRK2NPC1RAB9APTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4748236-A | Azo dyestuffs having sulpho ortho to azo bridge and containing two triazine reactive groups | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |
| US-4418015-A | Phthalocyanine reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1983-11-29 | — | — | US | disclosed |
| EP-0053320-A2 | Process for the preparation of phthalocyanin compounds | BAYER AG (DE) | 1982-06-09 | — | — | EP | disclosed |
| EP-0047863-A2 | Reactive phthalocyanine hyes, process for their preparation and their use in dyeing materials containing hydroxyle groups and/or nitrogen | BAYER AG (DE) | 1982-03-24 | — | — | EP | disclosed |
| US-4280956-A | CONTAINING SULFONAMIDE GROUPS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-07-28 | — | — | US | disclosed |