Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 2/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | CDK9 | P50750 | 2/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531321 | 0.87 | FUT8 (0.42) | LRRK2CA1CA2SNCANPC1 | |
| SCHEMBL9422589 | 0.76 | LRRK2 (0.45) | LRRK2CA1CA2SNCACDK2 | |
| SCHEMBL11315254 | 0.71 | LRRK2 (0.41) | LRRK2CA1CA2CDK2CHAT | |
| SCHEMBL9009756 | 0.70 | CA2 (0.46) | LRRK2CA1CA2NPC1RAB9A | |
| SCHEMBL11532173 | 0.69 | CA1 (0.34) | CA1CA2SNCAPOLBSCN1A | |
| SCHEMBL10621640 | 0.69 | CASR (0.44) | LRRK2NPC1RAB9ASMN1; SMN2TNNI3K | |
| SCHEMBL18902955 | 0.67 | TNNI3K (0.40) | LRRK2CA1CA2SNCATNNI3K | |
| SCHEMBL11134269 | 0.66 | PTK2 (0.43) | LRRK2TNNI3KPTK2AURKB | |
| SCHEMBL7718715 | 0.65 | LRRK2 (0.40) | LRRK2CA1CA2SNCA | |
| SCHEMBL27410410 | 0.65 | DAPK3 (0.46) | CA1CA2SNCACDC7DAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141890-A | FIBER-REACTIVE | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | claimed |
| US-4092308-A | 4-Sulphomethyl substituted hydroxypyridone azo dyestuffs | CIBA-GEIGY CORPORATION (US) | 1978-05-30 | — | — | US | claimed |