Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 10/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.43 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.43 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11135444 | 0.85 | PTK2 (0.43) | PTK2LRRK2EPHB4TNNI3KFGFR1 | |
| SCHEMBL10621640 | 0.83 | CASR (0.44) | PTK2LRRK2EPHB4TNNI3K | |
| SCHEMBL11856695 | 0.75 | ALDH1A1 (0.46) | — | |
| SCHEMBL10621652 | 0.75 | PTK2 (0.42) | PTK2LRRK2EPHB4TNNI3KFGFR1 | |
| SCHEMBL5082248 | 0.74 | ALDH1A1 (0.44) | — | |
| SCHEMBL11131894 | 0.72 | CDK2 (0.37) | PTK2LRRK2TNNI3K | |
| SCHEMBL10621767 | 0.70 | PTK2 (0.42) | PTK2LRRK2EPHB4FGFR1FGFR2 | |
| SCHEMBL14614602 | 0.70 | CA1 (0.38) | PTK2LRRK2TNNI3KFGFR1FGFR2 | |
| SCHEMBL11344310 | 0.68 | NT5E (0.41) | — | |
| SCHEMBL18902955 | 0.68 | TNNI3K (0.40) | LRRK2TNNI3K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4418015-A | Phthalocyanine reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1983-11-29 | — | — | US | disclosed |
| EP-0053320-A2 | Process for the preparation of phthalocyanin compounds | BAYER AG (DE) | 1982-06-09 | — | — | EP | disclosed |
| EP-0047863-A2 | Reactive phthalocyanine hyes, process for their preparation and their use in dyeing materials containing hydroxyle groups and/or nitrogen | BAYER AG (DE) | 1982-03-24 | — | — | EP | disclosed |
| US-4280956-A | CONTAINING SULFONAMIDE GROUPS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-07-28 | — | — | US | disclosed |