SCHEMBL106226

SCHEMBL106226

C1=CC2CC1CC2Cc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.51
TSHR P16473 2/20 0.51
ALDH1A1 P00352 7/20 0.51
TDP1 Q9NUW8 3/20 0.51
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
HTT P42858 1/20 0.41
PKM P14618 1/20 0.41
GBA1 P04062 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5377178 0.90 KDM4E (0.47) KDM4ETSHRALDH1A1TDP1KMT2A
SCHEMBL18586975 0.90 KDM4E (0.47) KDM4ETSHRALDH1A1TDP1KMT2A
SCHEMBL12964150 0.85 KDM4E (0.43) KDM4ETSHRALDH1A1TDP1KMT2A
SCHEMBL29738712 0.85 KDM4E (0.44) KDM4ETSHRALDH1A1TDP1KMT2A
SCHEMBL21525758 0.85 KDM4E (0.44) KDM4ETSHRALDH1A1TDP1KMT2A
SCHEMBL9112636 0.85 ALDH1A1 (0.40) KDM4ETSHRALDH1A1TDP1KMT2A
SCHEMBL12191679 0.81 KDM4E (0.46) KDM4ETSHRALDH1A1TDP1KMT2A
SCHEMBL145617 0.81 KDM4E (0.49) KDM4ETSHRALDH1A1TDP1KMT2A
SCHEMBL12512715 0.81 KDM4E (0.42) KDM4ETSHRALDH1A1TDP1KMT2A
SCHEMBL15367747 0.81 KDM4E (0.42) KDM4ETSHRALDH1A1TDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1363 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2970522-B1 IN-MOLD COATING OF ROMP POLYMERS MATERIA INC (US) 2025-05-21 EP claimed
EP-4504803-A1 PALLADIUM CATALYSTS FOR FORMING VINYL ADDITION POLYMERS HAVING IMPROVED FILM FORMING PROPERTIES Promerus, LLC (US) 2025-02-12 EP claimed
CN-119137161-A Palladium catalyst for vinyl addition polymer formation with improved film forming properties 普罗米鲁斯有限责任公司 2024-12-13 CN claimed
CN-119101214-A Cycloolefin metathesis composition and polymerization method thereof 道生天合材料科技(上海)股份有限公司 2024-12-10 CN claimed
US-12043573-B2 Adhesion promoters and gel-modifiers for olefin metathesis compositions MATERIA, INC. (US) 2024-07-23 US claimed
US-20240043608-A1 METHOD AND COMPOSITION FOR IMPROVING ADHESION OF METATHESIS COMPOSITIONS TO SUBSTRATES MATERIA, INC. (US) 2024-02-08 US claimed
EP-3053954-B1 MODIFIED OLEFIN RESIN LG CHEMICAL LTD (KR) 2023-12-06 EP claimed
EP-3256505-B1 CYCLIC OLEFIN RESIN COMPOSITIONS COMPRISING FUNCTIONAL ELASTOMERS MATERIA INC (US) 2023-11-29 EP claimed
WO-2023196366-A1 PALLADIUM CATALYSTS FOR FORMING VINYL ADDITION POLYMERS HAVING IMPROVED FILM FORMING PROPERTIES PROMERUS, LLC (US) 2023-10-12 WO claimed
US-20230312775-A1 PALLADIUM CATALYSTS FOR FORMING VINYL ADDITION POLYMERS HAVING IMPROVED FILM FORMING PROPERTIES PROMERUS, LLC (US) 2023-10-05 US claimed
US-20160046657-A1 ORGANOPALLADIUM COMPOUNDS AS POLYMERIZATION CATALYSTS SUMITOMO BAKELITE CO., LTD. (JP) 2016-02-18 US claimed
EP-2721106-A2 ADHESION PROMOTERS AND GEL-MODIFIERS FOR OLEFIN METATHESIS COMPOSITIONS Materia, Inc. (US) 2014-04-23 EP claimed
WO-2012174502-A2 ADHESION PROMOTERS AND GEL-MODIFIERS FOR OLEFIN METATHESIS COMPOSITIONS MATERIA, INC. (US) 2012-12-20 WO claimed
US-6811846-B1 THREE- OR FIVE-LAYERED LAMINATED PLASTIC MOLDED BODY HAVING POLYETHYLENE TEREPHTHALATE LAYERS LAMINATED ALTERNATELY WITH POLYOLEFIN RESIN LAYERS HAVING CYCLIC OLEFIN COMPONENT; TRANSPARENT, OIL RESISTANT, VAPOR BARRIER PROPERTIES YOSHINO KOGYOSHO CO., LTD. (JP) 2004-11-02 US claimed
US-6627714-B2 Copolymerizing ethylene and dicyclopentadiene or tricyclopentadiene, and cyclic olefin in presence of metallocene catalyst to produce copolymer MARUZEN PETROCHEMICAL CO., LTD. (JP) 2003-09-30 US claimed
US-6451946-B1 Copolymer, process for the production thereof, and molded article thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-17 US claimed
EP-0997141-A1 COSMETIC COMPOSITION CONTAINING AT LEAST ONE AMORPHOUS POLYCYCLOOLEFINE OR A MIXTURE AND THEIR USE L'OREAL (FR) 2000-05-03 EP claimed
EP-0446051-B1 Process for the production of cycloolefin-based random copolymer MITSUI PETROCHEMICAL IND (JP) 1995-11-15 EP claimed
US-5142007-A Copolymerizing with ethylene and at least one unsaturated monomer in presence of catalysts and mixed solvent MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-08-25 US claimed
EP-0446051-A1 Process for the production of cycloolefin-based random copolymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-09-11 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160046657-A1 ORGANOPALLADIUM COMPOUNDS AS POLYMERIZATION CATALYSTS MVD, DDT, CDV3 KDM4E 1705/4885TSHR 4854/4885ALDH1A1 1284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.