Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL106226 | 0.85 | KDM4E (0.51) | ALDH1A1KDM4ETDP1TSHRSMN1; SMN2 | |
| SCHEMBL23022892 | 0.79 | HTR2C (0.53) | TDP1MEN1KMT2A | |
| SCHEMBL18586975 | 0.76 | KDM4E (0.47) | ALDH1A1KDM4ETDP1TSHRMEN1 | |
| SCHEMBL5377178 | 0.75 | KDM4E (0.47) | ALDH1A1KDM4ETDP1TSHRSMN1; SMN2 | |
| SCHEMBL21196838 | 0.72 | SLC18A2 (0.40) | — | |
| SCHEMBL12964150 | 0.72 | KDM4E (0.43) | ALDH1A1KDM4ETDP1TSHRSMN1; SMN2 | |
| SCHEMBL29738712 | 0.72 | KDM4E (0.44) | ALDH1A1KDM4ETDP1TSHRSMN1; SMN2 | |
| SCHEMBL21525758 | 0.72 | KDM4E (0.44) | ALDH1A1KDM4ETDP1TSHRSMN1; SMN2 | |
| SCHEMBL29092813 | 0.69 | GBA1 (0.38) | ALDH1A1TSHRSMN1; SMN2GBA1 | |
| SCHEMBL7718211 | 0.69 | KDM4E (0.32) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655053-A1 | BICYCLOOCTANE AND BICYCLOHEPTANE DERIVATIVES. | BLACK JAMES FOUNDATION (GB) | 1995-05-31 | — | — | EP | disclosed |