Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.30 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.30 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.30 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.30 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.30 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.30 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10776251 | 0.79 | KDM4E (0.38) | GRM5KDM4EALDH1A1MAPTPRKCI | |
| SCHEMBL13715689 | 0.77 | KDM4E (0.49) | KDM4EALDH1A1MAPTPRKCI | |
| SCHEMBL10593982 | 0.76 | TDP1 (0.33) | GRM5KDM4EALDH1A1MAPTPRKCI | |
| SCHEMBL12411093 | 0.75 | SCD (0.37) | GRM5LRRK2KDM4EALDH1A1MAPT | |
| SCHEMBL10595043 | 0.73 | PIM1 (0.41) | GRM5ALDH1A1MAPT | |
| SCHEMBL10937760 | 0.72 | KIT (0.45) | GRM5KDM4EALDH1A1MAPT | |
| SCHEMBL13715949 | 0.70 | RAB9A (0.35) | KDM4EALDH1A1MAPT | |
| SCHEMBL10366750 | 0.70 | GRM5 (0.39) | GRM5ALDH1A1 | |
| SCHEMBL7996780 | 0.70 | MAPK1 (0.42) | GRM5LRRK2 | |
| SCHEMBL30610259 | 0.70 | MAPK1 (0.42) | GRM5LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792547-A | Pyrazine-2-carboxamide derivatives useful in treating allergic disease | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1988-12-20 | — | — | US | claimed |