Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14088941 | 0.87 | ALDH1A1 (0.52) | TSHRALDH1A1TDP1MAPTMAPK1 | |
| SCHEMBL2105183 | 0.81 | TSHR (0.61) | TSHRALDH1A1TDP1MAPTMAPK1 | |
| SCHEMBL3305172 | 0.78 | MAPT (0.51) | TSHRALDH1A1TDP1MAPTMAPK1 | |
| SCHEMBL30613334 | 0.78 | MAPT (0.51) | TSHRALDH1A1TDP1MAPTMAPK1 | |
| SCHEMBL18415443 | 0.78 | ALDH1A1 (0.53) | TSHRALDH1A1TDP1MAPTMAPK1 | |
| SCHEMBL10499633 | 0.78 | TDP1 (0.47) | TSHRALDH1A1TDP1MAPTMAPK1 | |
| SCHEMBL17997748 | 0.78 | ALDH1A1 (0.50) | TSHRALDH1A1TDP1MAPTMAPK1 | |
| SCHEMBL768569 | 0.77 | ALDH1A1 (0.60) | TSHRALDH1A1TDP1MAPTMAPK1 | |
| SCHEMBL1772369 | 0.77 | ALDH1A1 (0.50) | TSHRALDH1A1TDP1MAPTL3MBTL1 | |
| SCHEMBL10879675 | 0.77 | ALDH1A1 (0.59) | TSHRALDH1A1TDP1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4736067-A | DIRECT AND OXIDATION HAIR DYES | L'OREAL (FR) | 1988-04-05 | — | — | US | disclosed |