Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14088941 | 0.89 | ALDH1A1 (0.52) | ALDH1A1HSD17B10GPR35ADRA2AADRA2B | |
| SCHEMBL18676404 | 0.89 | GPR35 (0.56) | ALDH1A1HSD17B10GPR35ADRA2AADRA2B | |
| SCHEMBL19790249 | 0.83 | ALDH1A1 (0.46) | ALDH1A1HSD17B10GPR35ADRA2AADRA2B | |
| SCHEMBL14234731 | 0.79 | GPR35 (0.43) | ALDH1A1HSD17B10GPR35ADRA2AADRA2B | |
| SCHEMBL7711324 | 0.79 | ALDH1A1 (0.61) | ALDH1A1HSD17B10GPR35ADRA2AADRA2B | |
| SCHEMBL7520916 | 0.77 | KMT2A (0.55) | ALDH1A1GPR35KMT2AMEN1LMNA | |
| SCHEMBL10623045 | 0.77 | TSHR (0.52) | ALDH1A1HSD17B10GPR35RECQLTSHR | |
| SCHEMBL3305172 | 0.77 | MAPT (0.51) | ALDH1A1HSD17B10GPR35RECQLTSHR | |
| SCHEMBL30613334 | 0.77 | MAPT (0.51) | ALDH1A1HSD17B10GPR35RECQLTSHR | |
| SCHEMBL11291584 | 0.76 | ALDH1A1 (0.55) | ALDH1A1HSD17B10GPR35ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055213-B1 | PHENYL UREAS | CIBA-GEIGY AG (CH) | 1986-02-26 | — | — | EP | disclosed |
| US-4431671-A | SUBSTITUTED N-(P-AMINOPHENYL)-N'-BENZOYLUREAS; INSECTICIDES; PARASITICIDES; PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1984-02-14 | — | — | US | disclosed |
| EP-0055213-A2 | Phenyl ureas | CIBA-GEIGY AG (CH) | 1982-06-30 | — | — | EP | disclosed |