Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22739037 | 0.83 | SMN1; SMN2 (0.42) | LMNAHTTMEN1KMT2ATTR | |
| SCHEMBL9355391 | 0.77 | KMT2A (0.38) | LMNAHTTMEN1KMT2ATTR | |
| SCHEMBL26299717 | 0.73 | MAOA (0.46) | LMNAHTTMEN1KMT2ATTR | |
| SCHEMBL13657752 | 0.72 | HTT (0.33) | LMNAHTTMEN1KMT2ATTR | |
| SCHEMBL9136909 | 0.71 | CES1 (0.38) | LMNAHTTMEN1KMT2ATTR | |
| SCHEMBL13636983 | 0.71 | — | — | |
| SCHEMBL29390564 | 0.71 | MAOA (0.60) | LMNAHTTMEN1KMT2ATTR | |
| SCHEMBL482716 | 0.71 | MAOA (0.60) | LMNAHTTMEN1KMT2ATTR | |
| SCHEMBL4571020 | 0.71 | MAOA (0.60) | LMNAHTTMEN1KMT2ATTR | |
| SCHEMBL9505061 | 0.70 | TRPA1 (0.42) | HTTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4750228-A | Disperse dyes | CIBA-GEIGY CORPORATION (US) | 1988-06-14 | — | — | US | disclosed |
| EP-0258180-A2 | Disperse dyes | CIBA-GEIGY AG (CH) | 1988-03-02 | — | — | EP | disclosed |