Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | USP2 | O75604 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9355391 | 0.74 | KMT2A (0.38) | CES1TTREPHX2MEN1MAPT | |
| SCHEMBL9135452 | 0.71 | CES1 (0.40) | CES1TTRMEN1MAPTKMT2A | |
| SCHEMBL10623284 | 0.71 | LMNA (0.50) | CES1TTREPHX2MEN1MAPT | |
| SCHEMBL13683810 | 0.71 | KMT2A (0.45) | CES1TTREPHX2MEN1MAPT | |
| SCHEMBL23337592 | 0.70 | ILF3 (0.39) | CES1TTREPHX2MEN1MAPT | |
| SCHEMBL10036025 | 0.69 | KMT2A (0.54) | MEN1MAPTKMT2AUSP2RAB9A | |
| SCHEMBL13683624 | 0.67 | TRPA1 (0.40) | CES1TTREPHX2MEN1MAPT | |
| SCHEMBL13683627 | 0.67 | EPHX2 (0.33) | CES1TTREPHX2MEN1MAPT | |
| SCHEMBL13683621 | 0.67 | L3MBTL1 (0.50) | CES1TTREPHX2MEN1MAPT | |
| SCHEMBL6518017 | 0.66 | BRPF1 (0.53) | CES1TTRMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405968-A | Useful as drugs, for producing singlet oxygen, sensitizers in electrophotographic layers and for photopolymerizations and as laser light sensitive dyes in optical recording media | BASF AKTIENGESELLSCHAFT (DE) | 1995-04-11 | — | — | US | disclosed |