Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.55 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.52 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.52 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.52 |
| ▸ | GAPDH | P04406 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | STAT6 | P42226 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746201 | 0.86 | ADORA3 (0.52) | ALDH1A1SMN1; SMN2HTTBLMKDM4E | |
| SCHEMBL9699120 | 0.85 | ADORA3 (0.51) | ALDH1A1SMN1; SMN2HTTBLMKDM4E | |
| SCHEMBL11472440 | 0.85 | TP53 (0.62) | ALDH1A1SMN1; SMN2HTTBLMKDM4E | |
| SCHEMBL9619994 | 0.85 | TP53 (0.62) | ALDH1A1SMN1; SMN2HTTBLMKDM4E | |
| SCHEMBL9699971 | 0.85 | ADORA3 (0.51) | ALDH1A1SMN1; SMN2HTTBLMKDM4E | |
| SCHEMBL6934040 | 0.85 | TP53 (0.62) | ALDH1A1SMN1; SMN2HTTBLMKDM4E | |
| SCHEMBL9697576 | 0.83 | ADORA3 (0.49) | ALDH1A1SMN1; SMN2HTTBLMKDM4E | |
| SCHEMBL10623372 | 0.82 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HTTBLMKDM4E | |
| SCHEMBL10483440 | 0.81 | SLC29A1 (0.69) | ALDH1A1SMN1; SMN2HTTADORA3ADORA1 | |
| SCHEMBL9698667 | 0.81 | ADORA3 (0.47) | ALDH1A1SMN1; SMN2HTTBLMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155164-B1 | NOVEL CYANOIMIDAZOLE NUCLEOSIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-11-17 | — | — | EP | claimed |
| US-4728729-A | ANTITUMOR, IMMUNOSUPPRESSANT | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1988-03-01 | — | — | US | claimed |
| EP-0155164-A2 | Novel cyanoimidazole nucleoside derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1985-09-18 | — | — | EP | claimed |
| EP-0155164-B1 | NOVEL CYANOIMIDAZOLE NUCLEOSIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-11-17 | — | — | EP | disclosed |
| US-4728729-A | ANTITUMOR, IMMUNOSUPPRESSANT | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1988-03-01 | — | — | US | disclosed |
| EP-0155164-A2 | Novel cyanoimidazole nucleoside derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1985-09-18 | — | — | EP | disclosed |