Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HBB | P68871 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619994 | 1.00 | TP53 (0.62) | TP53KDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL11472440 | 1.00 | TP53 (0.62) | TP53KDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL10623398 | 0.85 | ALDH1A1 (0.60) | TP53KDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL5746201 | 0.85 | ADORA3 (0.52) | TP53KDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL9699120 | 0.84 | ADORA3 (0.51) | TP53KDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL9699971 | 0.84 | ADORA3 (0.51) | TP53KDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL9697576 | 0.82 | ADORA3 (0.49) | TP53KDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL6674912 | 0.82 | ADORA2A (0.57) | TP53KDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL9698515 | 0.80 | ADORA3 (0.50) | TP53KDM4ETDP1MAPTALDH1A1 | |
| SCHEMBL9698667 | 0.80 | ADORA3 (0.47) | TP53KDM4ETDP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0967220-B1 | Novel arabinosyladenine derivatives | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-6242429-B1 | ANTIVIRAL ARA-A DERIVATIVES HAVING RESISTANCE TO METABOLISM BY ADENOSINEDEAMINASE | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0967220-A1 | Novel arabinosyladenine derivatives | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1999-12-29 | — | — | EP | disclosed |