Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 9/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.59 |
| ▸ | ESRRG | P62508 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ESRRB | O95718 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10820851 | 0.89 | NR1H4 (0.58) | NR1H4EPHX2ESRRGRAB9ANPC1 | |
| SCHEMBL4692558 | 0.84 | RAB9A (0.63) | NR1H4EPHX2ESRRGRAB9ANPC1 | |
| SCHEMBL10629599 | 0.83 | NR1H4 (0.57) | NR1H4EPHX2ESRRGRAB9ANPC1 | |
| SCHEMBL10629576 | 0.75 | CYP4F2 (0.58) | NR1H4EPHX2ESRRGRAB9ANPC1 | |
| SCHEMBL2657987 | 0.74 | NR1H4 (0.59) | NR1H4EPHX2ESRRGRAB9ANPC1 | |
| SCHEMBL10349518 | 0.73 | MEN1 (0.53) | RAB9ANPC1CA1CA2MEN1 | |
| SCHEMBL11107537 | 0.72 | KDM4E (0.80) | HDAC6CA1CA2KMT2A | |
| SCHEMBL11828934 | 0.72 | ESRRG (0.49) | NR1H4EPHX2ESRRGRAB9ANPC1 | |
| SCHEMBL22651514 | 0.72 | ESRRG (0.49) | NR1H4EPHX2ESRRGRAB9ANPC1 | |
| SCHEMBL8829626 | 0.72 | RXRA (0.56) | NR1H4EPHX2ESRRGRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778925-A | ANTILIPEMIC AGENTS | KLINGE PHARMA GMBH (DE) | 1988-10-18 | — | — | US | disclosed |