Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.57 |
| ▸ | RXRA | P19793 | 2/20 | 0.56 |
| ▸ | RXRB | P28702 | 2/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | RARB | P10826 | 1/20 | 0.53 |
| ▸ | RARG | P13631 | 1/20 | 0.53 |
| ▸ | ESRRG | P62508 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | ESRRB | O95718 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lifibrol SCHEMBL9484778 | 0.87 | NR4A2 (0.64) | NR1H4EPHX2SRD5A2RXRARXRB | |
| SCHEMBL8829626 | 0.87 | RXRA (0.56) | NR1H4EPHX2SRD5A2RXRARXRB | |
| Lifibrol SCHEMBL140583 | 0.87 | NR4A2 (0.64) | NR1H4EPHX2SRD5A2RXRARXRB | |
| Lifibrol SCHEMBL9478310 | 0.87 | NR4A2 (0.64) | NR1H4EPHX2SRD5A2RXRARXRB | |
| SCHEMBL9414680 | 0.87 | MMP12 (0.54) | RARBMMP12MMP13 | |
| SCHEMBL10625366 | 0.83 | NR1H4 (0.59) | NR1H4EPHX2ESRRGNPC1RAB9A | |
| SCHEMBL10625370 | 0.81 | RXRA (0.53) | NR1H4EPHX2SRD5A2RXRARXRB | |
| SCHEMBL10629576 | 0.81 | CYP4F2 (0.58) | NR1H4EPHX2NR4A2ESRRGNPC1 | |
| SCHEMBL17699395 | 0.81 | SRD5A2 (0.61) | NR1H4EPHX2SRD5A2RXRARXRB | |
| SCHEMBL10629555 | 0.79 | RXRA (0.57) | RXRARXRBRARBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778925-A | ANTILIPEMIC AGENTS | KLINGE PHARMA GMBH (DE) | 1988-10-18 | — | — | US | disclosed |