Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.35 |
| ▸ | PGR | P06401 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11675295 | 0.87 | AR (0.33) | ARPGRNR3C2 | |
| SCHEMBL10952489 | 0.74 | ESR1 (0.59) | ARPGRESR1CHRM2ACHE | |
| SCHEMBL11511651 | 0.73 | ESR1 (0.58) | ARPGRESR1CHRM2ACHE | |
| SCHEMBL1901373 | 0.72 | ALDH1A1 (0.42) | ARPGRCYP2C19CYP19A1CYP3A4 | |
| SCHEMBL10956513 | 0.72 | SHBG (0.39) | ARESR1CYP19A1CYP3A4GRIN1 | |
| SCHEMBL10955197 | 0.70 | AR (0.42) | ARPGRESR1CHRM2ACHE | |
| SCHEMBL13474752 | 0.68 | AR (0.49) | ARPGRCYP2C19NR3C2CYP19A1 | |
| SCHEMBL29335494 | 0.68 | AR (0.51) | ARPGRCYP2C19NR3C2CYP19A1 | |
| SCHEMBL29335775 | 0.68 | AR (0.51) | ARPGRCYP2C19NR3C2CYP19A1 | |
| SCHEMBL2833823 | 0.68 | AR (0.51) | ARPGRCYP2C19NR3C2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4720357-A | New process for manufacturing derivatives of 17 alpha-hydroxy 19-nor progesterone and novel intermediates for use therein | LABORATOIRE THERAMEX (MC) | 1988-01-19 | — | — | US | claimed |
| US-4720357-A | New process for manufacturing derivatives of 17 alpha-hydroxy 19-nor progesterone and novel intermediates for use therein | LABORATOIRE THERAMEX (MC) | 1988-01-19 | — | — | US | disclosed |