Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6393101 | 0.81 | ALDH1A1 (0.41) | AGPAT2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL14097365 | 0.76 | HDAC6 (0.49) | ALDH1A1KDM4EHSD17B10HDAC6HTT | |
| SCHEMBL6393353 | 0.70 | KDM4E (0.44) | ALDH1A1KDM4EHPGDHSD17B10HTT | |
| SCHEMBL14097370 | 0.69 | LMNA (0.59) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL11840974 | 0.68 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDHSD17B10PKM | |
| SCHEMBL23610923 | 0.68 | ALDH1A1 (0.52) | ALDH1A1HPGDHDAC6TSHRHTT | |
| SCHEMBL11177029 | 0.68 | TSHR (0.64) | ALDH1A1KDM4EHSD17B10PKMTSHR | |
| SCHEMBL2092941 | 0.66 | SMN1; SMN2 (0.68) | ALDH1A1KDM4EHPGDHTTMEN1 | |
| SCHEMBL29145106 | 0.66 | KDR (0.50) | ALDH1A1KDM4EHPGDTSHRNR4A2 | |
| SCHEMBL2094875 | 0.66 | MGLL (0.68) | MEN1KMT2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792610-A | Process for the preparation of 5-phenylsulfinyl-1H-2-(methoxycarbonylamino)-benzimidazole | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-12-20 | — | — | US | claimed |
| US-4792610-A | Process for the preparation of 5-phenylsulfinyl-1H-2-(methoxycarbonylamino)-benzimidazole | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-12-20 | — | — | US | disclosed |
| US-4792610-A | Process for the preparation of 5-phenylsulfinyl-1H-2-(methoxycarbonylamino)-benzimidazole | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-12-20 | — | — | US | disclosed |
| US-3980796-A | CONTROL OF PARASITES AND NEMATODES | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-09-14 | — | — | US | disclosed |