Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.30 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.30 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258945 | 0.84 | THRB (0.47) | THRBTSHR | |
| SCHEMBL1498219 | 0.82 | TSHR (0.50) | THRBTSHRALDH1A1 | |
| Bromide SCHEMBL17536050 | 0.80 | TSHR (0.48) | THRBTSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL10629539 | 0.80 | THRB (0.50) | THRBTSHRALDH1A1 | |
| SCHEMBL28044392 | 0.80 | TSHR (0.48) | THRBTSHRALDH1A1 | |
| Iodide SCHEMBL21253234 | 0.80 | TSHR (0.48) | THRBTSHRALDH1A1 | |
| SCHEMBL1072477 | 0.80 | THRB (0.37) | THRBTSHRALDH1A1PPARDBTN3A1 | |
| SCHEMBL29199920 | 0.80 | THRB (0.58) | THRBTSHRALDH1A1BTN3A1LPAR3 | |
| SCHEMBL4937680 | 0.77 | TSHR (0.39) | THRBTSHRALDH1A1 | |
| SCHEMBL1982897 | 0.76 | BTN3A1 (0.37) | THRBTSHRPPARDBTN3A1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300990-B2 | A block copolymer of the A-B or A-B-A type in which A and B are different in which at least one of the A and B is formed from ethylenically unsaturated monomer including a zwitterionic monomer; is 2-methacryloyloxyethyl-2'-trimethylammonium ethyl phosphate inner salt as a monomer; for drug delivery | BIOCOMPATIBLES UK LIMITED (GB) | 2007-11-27 | — | — | US | disclosed |
| US-20050159556-A1 | Zwitterionic polymers | BIOCOMPATIBLES UK LIMITED | 2005-07-21 | — | — | US | disclosed |
| US-6852816-B2 | Zwitterionic polymers | BIOCOMPATIBLES UK LIMITED (GB) | 2005-02-08 | — | — | US | disclosed |
| US-20040063881-A1 | Zwitterionic polymers | BIOCOMPATIBLES UK LIMITED (GB) | 2004-04-01 | — | — | US | disclosed |
| EP-1325046-A1 | ZWITTERIONIC POLYMERS | Biocompatibles UK Limited (GB) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002028929-A1 | ZWITTERIONIC POLYMERS | BIOCOMPATIBLES UK LIMITED (GB) | 2002-04-11 | — | — | WO | disclosed |