Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Butyltriphenylphosphonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 8/20 | 0.41 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyltriphenylphosphonium SCHEMBL1063 | 0.98 | HIF1A (0.61) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL28007945 | 0.96 | HIF1A (0.58) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL2650050 | 0.96 | HIF1A (0.58) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL30358591 | 0.96 | HIF1A (0.64) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL2650095 | 0.94 | HIF1A (0.56) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL27985987 | 0.94 | HIF1A (0.56) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL28337794 | 0.94 | HIF1A (0.56) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL584744 | 0.93 | HIF1A (0.61) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL584160 | 0.93 | HIF1A (0.61) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Butyltriphenylphosphonium SCHEMBL3418099 | 0.93 | HIF1A (0.61) | HIF1AALDH1A1CYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107694602-B | A kind of synthetic method of the catalyst for preparing propylene glycol phenylate and propylene glycol phenylate | 佳化化学（茂名）有限公司 | 2019-11-12 | — | — | CN | claimed |
| CN-106035371-B | A kind of drinking water bactericidal ball based on shell microcellular structure | 杭州雪贝儿生物科技有限公司 | 2019-05-03 | — | — | CN | claimed |
| CN-109608697-A | A kind of modified MoS of phosphorus-containing compound2The preparation method and applications of nanoscale twins | 中国地质大学（武汉） | 2019-04-12 | — | — | CN | claimed |
| CN-106044980-B | A kind of compound water body fungicide | 杭州雪贝儿生物科技有限公司 | 2019-03-26 | — | — | CN | claimed |
| CN-106543423-B | Fatty poly-ester carbonate composite material and preparation method | 河南大学 | 2018-12-28 | — | — | CN | claimed |
| CN-106543424-B | A kind of poly (propylene carbonate)/POSS hybrid material and preparation method thereof | 河南大学 | 2018-11-30 | — | — | CN | claimed |
| CN-108910867-A | A kind of method of MPCVD preparation doping nitrogen phosphorus graphene | 恒力（厦门）石墨烯科技产业集团有限公司 | 2018-11-30 | — | — | CN | claimed |
| CN-108484531-A | A kind of synthesis technology of terephthalic acid diglycidyl ester | 江苏正丹化学工业股份有限公司 | 2018-09-04 | — | — | CN | claimed |
| CN-108410128-A | A kind of high-speed high frequency resin combination, prepreg and laminate used for printed circuit board | 浙江华正新材料股份有限公司 | 2018-08-17 | — | — | CN | claimed |
| CN-108383688-A | A kind of striped rice borer, the composition principle and its processing technology of yellow rice borer pheromones | 上海右肯医药科技有限公司 | 2018-08-10 | — | — | CN | claimed |
| CN-105152126-A | Preparation method of small-layer-number MoSe2 nanosheet/nitrogen and phosphorus co-doped graphene composite nanomaterial | UNIV LINGNAN NORMAL | 2015-12-16 | — | — | CN | claimed |
| CN-105161691-A | Preparation method of less-layer MoS2/phosphorus-doped graphene electrochemical sodium-storage combined electrode | UNIV LINGNAN NORMAL | 2015-12-16 | — | — | CN | claimed |
| CN-105001586-A | Electric conduction compound ABS/PLA material for 3D printing wires as well as preparation method and application of electric conduction compound ABS/PLA material | UNIV JINAN | 2015-10-28 | — | — | CN | claimed |
| CN-103012322-B | A kind of synthetic method of Racemic glycidol | GUANGZHOU STARTEC SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2015-09-30 | — | — | CN | claimed |
| CN-102964775-B | A kind of compositions of thermosetting resin and uses thereof | SHENGYI SCIENCE AND TECHNOLOGY CO., LTD, GUANGDONG (CN) | 2015-09-16 | — | — | CN | claimed |
| CN-104892902-A | Thermosetting resin composition and application thereof | SHENGYI TECHNOLOGY CO LTD | 2015-09-09 | — | — | CN | claimed |
| CN-104693080-A | Preparation method of 6-substituted-2-trifluoromethylbenzenesulfonyl chloride | NANJING LYNSCI CHEMICAL CO LTD | 2015-06-10 | — | — | CN | claimed |
| CN-103073701-B | Fatty acid modified epoxy resin and preparation method thereof | EPOXY BASE ELECTRONIC MATERIAL CORP LTD | 2015-04-01 | — | — | CN | claimed |
| CN-104403250-A | Methyl methacrylate resin with excellent thermal stability | SHANGHAI KUMHO SUNNY PLASTICS | 2015-03-11 | — | — | CN | claimed |
| CN-102993742-B | Preparation method and application of nylon6/66 composite material | TIANJIN KINGFA NEW MATERIAL TECHNOLOGY CO LTD | 2015-02-25 | — | — | CN | claimed |