Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10632868 | 0.86 | LMNA (0.47) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL11665608 | 0.84 | LMNA (0.48) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL11664786 | 0.79 | ASAH1 (0.60) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL4637559 | 0.77 | LMNA (0.61) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL10459087 | 0.77 | ASAH1 (0.72) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL11098174 | 0.77 | TYMP (0.44) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL10979556 | 0.77 | ASAH1 (0.65) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL11731941 | 0.76 | LMNA (0.50) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL11257605 | 0.76 | ASAH1 (0.57) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL11406796 | 0.76 | ASAH1 (0.67) | ASAH1LMNACYP3A4CYP2D6MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792607-A | ANTICANCER MEDICINE INTERRMEDIATES | CHISSO CORPORATION (JP) | 1988-12-20 | — | — | US | disclosed |
| EP-0240352-A2 | 5-Fluorouracil derivatives and processes for producing thereof | Chisso Corporation (JP) | 1987-10-07 | — | — | EP | disclosed |