Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10979556 | 0.93 | ASAH1 (0.65) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL11406796 | 0.91 | ASAH1 (0.67) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL11417003 | 0.87 | ASAH1 (0.56) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL11257605 | 0.81 | ASAH1 (0.57) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL17278298 | 0.81 | LMNA (0.69) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL11601229 | 0.80 | ASAH1 (0.80) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL9664618 | 0.80 | LMNA (0.67) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL11239635 | 0.79 | LMNA (0.70) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL9666342 | 0.79 | PABPC1 (0.55) | ASAH1LMNACYP3A4CYP2D6MAPK3 | |
| SCHEMBL10631409 | 0.79 | ASAH1 (0.53) | ASAH1LMNACYP3A4CYP2D6MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-53059680-A | — | — | None | — | — | JP | disclosed |
| WO-2017123823-A1 | ALKYL-, ACYL-, UREA-, AND AZA-URACIL SULFIDE:QUINONE OXIDOREDUCTASE INHIBITORS | BIOELECTRON TECHNOLOGY CORPORATION (US) | 2017-07-20 | — | — | WO | disclosed |
| JP-S5359680-A | 1-(N-ARALKYLCARBAMOYL)-5-FLUOROURACILS AND THEIR PREPARATION | MITSUI TOATSU CHEM INC | 1978-05-29 | — | — | JP | disclosed |