Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.78 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | YAP1 | P46937 | 1/20 | 0.42 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.42 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 7/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Etofenamate SCHEMBL25152 | 0.88 | LMNA (1.00) | LMNACYP1A2CYP2C9CYP2C19SIRT2 | |
| Etofenamate SCHEMBL6836167 | 0.84 | LMNA (0.92) | LMNACYP1A2CYP2C9CYP2C19SIRT2 | |
| SCHEMBL10631528 | 0.83 | LMNA (0.67) | LMNACYP1A2CYP2C9CYP2C19SIRT2 | |
| SCHEMBL28322767 | 0.82 | TSHR (0.56) | LMNACYP1A2CYP2C9CYP2C19SIRT2 | |
| SCHEMBL12715082 | 0.82 | LMNA (0.91) | LMNACYP1A2CYP2C9CYP2C19SIRT2 | |
| SCHEMBL22556586 | 0.82 | CDC25B (0.56) | LMNACYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL21765032 | 0.79 | MAPT (0.69) | LMNACYP1A2CYP2C9CYP2C19SIRT2 | |
| SCHEMBL27687313 | 0.77 | LMNA (0.58) | LMNACYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL207925 | 0.75 | TSHR (0.61) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL1532574 | 0.75 | TSHR (0.61) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4731384-A | ADJUVANTS, ANTIINFLAMMATORY AGENTS | TROPONWERKE GMBH & CO, KG (DE) | 1988-03-15 | — | — | US | claimed |