Etofenamate

Etofenamate

SCHEMBL25152

O=C(OCCOCCO)c1ccccc1Nc1cccc(C(F)(F)F)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 1.00
CYP1A2 P05177 1/20 1.00
CYP2C9 P11712 1/20 1.00
CYP2C19 P33261 1/20 1.00
YAP1 P46937 1/20 0.58
TEAD4 Q15561 1/20 0.58
TEAD2 Q15562 1/20 0.58
RXFP1 Q9HBX9 4/20 0.58
SIRT2 Q8IXJ6 2/20 0.52
MPO P05164 3/20 0.48
ALDH1A1 P00352 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
AKR1C3 P42330 1/20 0.46
AKR1C2 P52895 1/20 0.46
SLC6A2 P23975 1/20 0.46
HTR2A P28223 1/20 0.46
OPRK1 P41145 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Etofenamate SCHEMBL6836167 0.96 LMNA (0.92) LMNACYP1A2CYP2C9CYP2C19YAP1
SCHEMBL12715082 0.96 LMNA (0.91) LMNACYP1A2CYP2C9CYP2C19YAP1
SCHEMBL10631533 0.88 LMNA (0.78) LMNACYP1A2CYP2C9CYP2C19YAP1
Etofenamate SCHEMBL13731241 0.84 LMNA (0.71) LMNACYP1A2CYP2C9CYP2C19YAP1
Etofenamate SCHEMBL28086507 0.84 LMNA (0.71) LMNACYP1A2CYP2C9CYP2C19YAP1
SCHEMBL10310897 0.84 LMNA (0.72) LMNACYP1A2CYP2C9CYP2C19YAP1
Ufenamate SCHEMBL36095 0.83 CYP1A2 (0.72) LMNACYP1A2CYP2C9CYP2C19YAP1
Ufenamate SCHEMBL29376700 0.83 CYP1A2 (0.72) LMNACYP1A2CYP2C9CYP2C19YAP1
SCHEMBL10597386 0.83 LMNA (0.71) LMNACYP1A2CYP2C9CYP2C19YAP1
Etofenamate SCHEMBL28772901 0.83 LMNA (0.69) LMNACYP1A2CYP2C9CYP2C19YAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9477 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139030-A1 CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION SHATTUCK LABS INC (US) 2026-05-21 US claimed
CN-122031290-A Percutaneous permeation promoting system and preparation method and application thereof 北京工商大学 2026-05-15 CN claimed
US-20260069532-A1 METHOD FOR MORSELIZING AND/OR TARGETING PHARMACEUTICALLY ACTIVE PRINCIPLES TO SYNOVIAL TISSUE MEDINCELL S.A. (FR) 2026-03-12 US claimed
US-12558309-B2 Method for morselizing and/or targeting pharmaceutically active principles to synovial tissue MEDINCELL S.A. (FR) 2026-02-24 US claimed
US-20260000741-A1 METHOD OF AMELIORATING A PRO-INFLAMMATORY IMMUNOPHENOTYPE IN FARBER DISEASE SUBJECTS BY REPEATED ADMINISTRATION OF A RECOMBINANT HUMAN ACID CERAMIDASE ACERAGEN INC (US) 2026-01-01 US claimed
WO-2025224317-A1 A METHOD FOR TARGETING PHARMACEUTICALLY ACTIVE PRINCIPLE IN TOTAL KNEE REPLACEMENT MEDINCELL S.A. (FR) 2025-10-30 WO claimed
US-12427109-B2 Natural origin stabilizer for oil in water emulsions FUNDACIÓN CIDETEC (ES) 2025-09-30 US claimed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 EP claimed
CN-119757554-A High performance liquid chromatography-tandem mass spectrometry analysis method for simultaneously detecting 33 components of anti-inflammatory agent in cosmetics 四川省药品检验研究院(四川省医疗器械检测中心) 2025-04-04 CN claimed
WO-2025062440-A1 TOPICAL NANO-DISPERSION COMPOSITIONS AND THEIR PREPARATION THEREOF PULSE PHARMACEUTICALS PVT. LTD (IN) 2025-03-27 WO claimed
EP-0132690-B1 THERMOPLASTICS CONTAINING ANTIPHLOGISTICS Troponwerke GmbH & Co. KG (DE) 1989-02-01 EP claimed
EP-0285181-A2 Etofenamate-containing adhesive tape TEIKOKU SEIYAKU KABUSHIKI KAISHA (JP) 1988-10-05 EP claimed
US-4738670-A ELASTIC SHEET CONVERING RESERVOIR OR MEDICINE, ELASTOMER, CARRIER; CONTROLLED RELEASE THROUGH SKIN BAYER AKTIENGESELLSCHAFT (DE) 1988-04-19 US claimed
US-4734434-A N-(TRIFLUOROMETHYLPHENYL)ANTHRANILIC ACID ESTERS RORER PHARMACEUTICAL CORPORATION (US) 1988-03-29 US claimed
US-4731384-A ADJUVANTS, ANTIINFLAMMATORY AGENTS TROPONWERKE GMBH & CO, KG (DE) 1988-03-15 US claimed
US-4594357-A Depot antiinflammatory agents TROPONWERKE GMBH & CO. (DE) 1986-06-10 US claimed
US-4557934-A ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE THE PROCTER & GAMBLE COMPANY (US) 1985-12-10 US claimed
US-4537776-A PERCUTANEOUS DELIVERY OF ANTIINFLAMMATORY AGENTS THE PROCTER & GAMBLE COMPANY (US) 1985-08-27 US claimed
US-4455146-A THERMOPLASTIC ELASTOMERS, OILS OR FATTY ACID, TACKFIER, AND A MEDICINE HISAMITSU PHARMACEUTICAL CO., LTD. (JP) 1984-06-19 US claimed
EP-0103911-A1 Emollient-containing topical pharmaceutical compositions THE PROCTER & GAMBLE COMPANY (US) 1984-03-28 EP claimed