Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.92 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.92 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.92 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.92 |
| ▸ | YAP1 | P46937 | 1/20 | 0.54 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.54 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | MPO | P05164 | 6/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Etofenamate SCHEMBL25152 | 0.96 | LMNA (1.00) | LMNACYP1A2CYP2C9CYP2C19YAP1 | |
| SCHEMBL12715082 | 0.92 | LMNA (0.91) | LMNACYP1A2CYP2C9CYP2C19YAP1 | |
| SCHEMBL10631533 | 0.84 | LMNA (0.78) | LMNACYP1A2CYP2C9CYP2C19YAP1 | |
| Flufenamic Acid SCHEMBL29356958 | 0.82 | RXFP1 (0.75) | LMNACYP1A2CYP2C9YAP1TEAD4 | |
| Flufenamic Acid SCHEMBL17497 | 0.82 | RXFP1 (0.75) | LMNACYP1A2CYP2C9YAP1TEAD4 | |
| Etofenamate SCHEMBL13731241 | 0.82 | LMNA (0.71) | LMNACYP1A2CYP2C9CYP2C19YAP1 | |
| Etofenamate SCHEMBL28086507 | 0.82 | LMNA (0.71) | LMNACYP1A2CYP2C9CYP2C19YAP1 | |
| Flufenamic Acid SCHEMBL9845499 | 0.81 | RXFP1 (0.73) | LMNACYP1A2CYP2C9YAP1TEAD4 | |
| Flufenamic Acid SCHEMBL11524554 | 0.81 | RXFP1 (0.73) | LMNACYP1A2CYP2C9YAP1TEAD4 | |
| SCHEMBL10310897 | 0.81 | LMNA (0.72) | LMNACYP1A2CYP2C9CYP2C19YAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040115258-A1 | Oral pharmaceutical compositions containing cyclodextrins as taste masking agent | ELAN PHARMA SA (CH) | 2004-06-17 | — | — | US | disclosed |