Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.55 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10627732 | 0.88 | GABRA1 (0.52) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10630010 | 0.86 | GABRP (0.55) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10625515 | 0.84 | — | — | |
| SCHEMBL8802212 | 0.80 | GABRG2 (0.48) | GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL26083668 | 0.79 | GABRG2 (0.42) | GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10627744 | 0.79 | GABRA1 (0.52) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL16840702 | 0.78 | GABRG2 (0.47) | GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL15250816 | 0.78 | GABRG2 (0.46) | GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL26083731 | 0.77 | GABRG2 (0.41) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10632027 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4772696-A | CYCLIZATION USING ISONITRILE | A/S FERROSAN (DK) | 1988-09-20 | — | — | US | disclosed |
| US-4727153-A | NERVOUS SYSTEM DISORDERS | A/S FERROSAN (DK) | 1988-02-23 | — | — | US | disclosed |
| US-4670433-A | CARDIOVASCULAR DISORDERS | A/S FERROSAN (DK) | 1987-06-02 | — | — | US | disclosed |
| EP-0197282-A1 | Novel oxadiazolyl imidazobenzodiazepine derivatives and methods of preparing such compounds | A/S FERROSAN (DK) | 1986-10-15 | — | — | EP | disclosed |