Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10632586 | 1.00 | ALDH1A1 (0.61) | ALDH1A1MAPTPOLBSMN1; SMN2MEN1 | |
| SCHEMBL3249655 | 0.80 | ALDH1A1 (0.73) | ALDH1A1MAPTMEN1KMT2AHDAC1 | |
| SCHEMBL1459456 | 0.79 | ALDH1A1 (0.71) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL10639336 | 0.77 | ALDH1A1 (0.51) | ALDH1A1EPHX1ALOX12KDM4EMAPK1 | |
| SCHEMBL30707863 | 0.75 | ALDH1A1 (0.60) | ALDH1A1MAPTMEN1KMT2AEPHX1 | |
| SCHEMBL10896720 | 0.75 | ALDH1A1 (0.60) | ALDH1A1MAPTMEN1KMT2AEPHX1 | |
| SCHEMBL10632987 | 0.74 | SMN1; SMN2 (0.53) | ALDH1A1MAPTPOLBSMN1; SMN2MEN1 | |
| SCHEMBL10632992 | 0.74 | SMN1; SMN2 (0.53) | ALDH1A1MAPTPOLBSMN1; SMN2MEN1 | |
| SCHEMBL2388970 | 0.73 | EPHX1 (0.70) | ALDH1A1MAPTPOLBSMN1; SMN2MEN1 | |
| SCHEMBL21678186 | 0.72 | ALDH1A1 (0.60) | ALDH1A1MAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123254-B1 | TRIAZINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-22 | — | — | EP | disclosed |
| US-4618610-A | Triazine derivatives, and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-21 | — | — | US | disclosed |