Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10639342 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KDM4E | |
| SCHEMBL10632586 | 0.77 | ALDH1A1 (0.61) | ALDH1A1ALOX12KDM4EEPHX1MAPK1 | |
| SCHEMBL10632577 | 0.77 | ALDH1A1 (0.61) | ALDH1A1ALOX12KDM4EEPHX1MAPK1 | |
| SCHEMBL10811234 | 0.77 | CTSL (0.48) | LMNACYP1A2CYP2C19CTSL | |
| SCHEMBL10813077 | 0.75 | CTSL (0.68) | KDM4ECTSL | |
| SCHEMBL10812209 | 0.73 | CTSL (0.55) | CTSL | |
| SCHEMBL10808993 | 0.72 | CTSL (0.51) | ALDH1A1KDM4ECTSL | |
| SCHEMBL10813148 | 0.72 | CTSL (0.56) | CTSL | |
| SCHEMBL10812143 | 0.71 | ATM (0.63) | ALDH1A1GAACTSL | |
| SCHEMBL10846055 | 0.71 | CTSL (0.56) | ALDH1A1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123254-B1 | TRIAZINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-22 | — | — | EP | disclosed |
| US-4618610-A | Triazine derivatives, and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-21 | — | — | US | disclosed |
| EP-0123254-A1 | Triazine derivatives, processes for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-31 | — | — | EP | disclosed |