Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.57 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.57 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.57 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3782005 | 0.86 | KDM4E (0.68) | EPHX1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL29822237 | 0.84 | KDM4E (0.66) | EPHX1ALDH1A1KDM4EHSD17B10PDK1 | |
| SCHEMBL4311940 | 0.84 | KDM4E (0.66) | EPHX1ALDH1A1KDM4EHSD17B10PDK1 | |
| SCHEMBL11363389 | 0.83 | EPHX1 (1.00) | EPHX1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL30707863 | 0.82 | ALDH1A1 (0.60) | EPHX1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL21678186 | 0.82 | ALDH1A1 (0.60) | EPHX1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL10896720 | 0.82 | ALDH1A1 (0.60) | EPHX1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3791892 | 0.82 | ALDH1A1 (0.60) | EPHX1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL6106176 | 0.82 | GAA (0.63) | KMT2APOLBALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1249700 | 0.82 | KCNMA1 (0.64) | MEN1KMT2APOLBKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108290139-B | Process for the catalytic hydrogenation of halogenated nitroaromatics | 孟山都技术公司 | 2021-12-31 | — | — | CN | claimed |
| US-11820725-B2 | Process for catalytic hydrogenation of halonitroaromatics | MONSANTO TECHNOLOGY LLC (US) | 2023-11-21 | — | — | US | disclosed |
| US-20220098141-A1 | PROCESS FOR CATALYTIC HYDROGENATION OF HALONITROAROMATICS | MONSANTO TECHNOLOGY LLC (US) | 2022-03-31 | — | — | US | disclosed |
| US-11225454-B2 | Process for catalytic hydrogenation of halonitroaromatics | MONSANTO TECHNOLOGY LLC (US) | 2022-01-18 | — | — | US | disclosed |
| CN-108290139-B | Process for the catalytic hydrogenation of halogenated nitroaromatics | 孟山都技术公司 | 2021-12-31 | — | — | CN | disclosed |
| WO-2021155253-A1 | ANAT INHIBITORS AND METHODS OF USE THEREOF | Atomwise Inc. (US) | 2021-08-05 | — | — | WO | disclosed |
| EP-3204360-B1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH INC (US) | 2020-08-26 | — | — | EP | disclosed |
| US-20200223784-A1 | PROCESS FOR CATALYTIC HYDROGENATION OF HALONITROAROMATICS | MONSANTO TECHNOLOGY LLC (US) | 2020-07-16 | — | — | US | disclosed |
| US-10562841-B2 | Process for catalytic hydrogenation of halonitroaromatics | MONSANTO TECHNOLOGY LLC (US) | 2020-02-18 | — | — | US | disclosed |
| US-20170312292-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | WUXI APPTEC (SHANGHAI) CO. LTD (CN) | 2017-11-02 | — | — | US | disclosed |
| EP-0128006-A2 | A soil-disease-controlling agent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-12-12 | — | — | EP | disclosed |
| EP-0023557-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED NITROARYL COMPOUNDS | CIBA-GEIGY AG (CH) | 1984-08-01 | — | — | EP | disclosed |
| EP-0049711-B1 | PROCESS FOR THE PRODUCTION OF NITRO-AMINO-BENZENES | BAYER AG (DE) | 1984-02-29 | — | — | EP | disclosed |
| EP-0028203-B1 | PROCESS FOR CARRYING OFF THE REACTION HEAT FROM EXOTHERMAL CHEMICAL REACTIONS AND APPARATUS FOR CARRYING OUT THE PROCESS | CIBA-GEIGY AG (CH) | 1982-12-15 | — | — | EP | disclosed |
| US-4339618-A | Process for the production of substituted nitroaryl compounds | CIBA-GEIGY AG (CH) | 1982-07-13 | — | — | US | disclosed |
| EP-0049711-A1 | Process for the production of nitro-amino-benzenes | BAYER AG (DE) | 1982-04-21 | — | — | EP | disclosed |
| EP-0023557-A1 | Process for the preparation of substituted nitroaryl compounds | CIBA-GEIGY AG (CH) | 1981-02-11 | — | — | EP | disclosed |
| US-4151203-A | Process for the preparation of p-nitroaniline compounds by the alkaline hydrolysis of mixed anilides | EASTMAN KODAK COMPANY (US) | 1979-04-24 | — | — | US | disclosed |
| US-4102924-A | REACTING ACYLAMINO-ARYLS WITH HALO-ARYLS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-25 | — | — | US | disclosed |
| US-4019857-A | Process for the coloration of hydrophobic chemical fibers by metalliferous dyestuffs of cationic character | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1977-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11225454-B2 | Process for catalytic hydrogenation of halonitroaromatics | HDHD5, HPD, HAO2 | EPHX1 2152/4885MEN1 757/4885KMT2A 441/4885 |
| US-11820725-B2 | Process for catalytic hydrogenation of halonitroaromatics | HDHD5, HPD, HAO2 | EPHX1 2152/4885MEN1 757/4885KMT2A 441/4885 |
| US-10562841-B2 | Process for catalytic hydrogenation of halonitroaromatics | HDHD5, HPD, HAO2 | EPHX1 2152/4885MEN1 757/4885KMT2A 441/4885 |
| US-20170312292-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | EP300, CREBBP, HDAC1 | EPHX1 1522/4885MEN1 1807/4885KMT2A 264/4885 |
| US-20200223784-A1 | PROCESS FOR CATALYTIC HYDROGENATION OF HALONITROAROMATICS | HDHD5, HPD, HAO2 | EPHX1 2152/4885MEN1 757/4885KMT2A 441/4885 |
| US-20220098141-A1 | PROCESS FOR CATALYTIC HYDROGENATION OF HALONITROAROMATICS | HDHD5, HPD, HAO2 | EPHX1 2152/4885MEN1 757/4885KMT2A 441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.