Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.60 |
| ▸ | TFEB | P19484 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10634703 | 1.00 | NFE2L2 (0.60) | NFE2L2TFEBKDM4EALDH1A1HPGD | |
| SCHEMBL10990878 | 0.84 | NFE2L2 (0.70) | NFE2L2TFEBKDM4EALDH1A1HPGD | |
| SCHEMBL4775241 | 0.82 | KDM4E (0.67) | NFE2L2TFEBKDM4EALDH1A1HPGD | |
| SCHEMBL31506312 | 0.82 | KDM4E (0.67) | NFE2L2TFEBKDM4EALDH1A1HPGD | |
| SCHEMBL15188 | 0.82 | KDM4E (0.67) | NFE2L2TFEBKDM4EALDH1A1HPGD | |
| SCHEMBL13957562 | 0.82 | KDM4E (0.67) | NFE2L2TFEBKDM4EALDH1A1HPGD | |
| SCHEMBL9581017 | 0.81 | KDM4E (0.47) | NFE2L2TFEBKDM4EALDH1A1HPGD | |
| SCHEMBL9581018 | 0.81 | KDM4E (0.47) | NFE2L2TFEBKDM4EALDH1A1HPGD | |
| SCHEMBL19244433 | 0.80 | KDM4E (0.72) | NFE2L2TFEBKDM4EALDH1A1HPGD | |
| SCHEMBL2474892 | 0.80 | KDM4E (0.72) | NFE2L2TFEBKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4767782-A | Propargyl cinnamates, their preparation and their use for controlling pests | BASF AKTIENGESELLSCHAFT (DE) | 1988-08-30 | — | — | US | disclosed |