Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CAMKK2 | Q96RR4 | 9/20 | 0.46 |
| ▸ | CAMKK1 | Q8N5S9 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | BRS3 | P32247 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10634926 | 1.00 | KDM4E (0.53) | KDM4ETDP1CAMKK2CAMKK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10630457 | 0.99 | KDM4E (0.51) | KDM4ETDP1CAMKK2CAMKK1ALDH1A1 | |
| SCHEMBL4827148 | 0.83 | ALDH1A1 (0.51) | CAMKK2CAMKK1ALDH1A1GAAPTGDR2 | |
| SCHEMBL8774864 | 0.81 | PTGDR2 (0.48) | CAMKK2CAMKK1ALDH1A1GAAPTGDR2 | |
| SCHEMBL9265839 | 0.81 | KDM4E (0.74) | KDM4ETDP1ALDH1A1GAAMAPT | |
| SCHEMBL10628736 | 0.79 | KDM4E (0.50) | KDM4ETDP1ALDH1A1GAABRS3 | |
| SCHEMBL50486 | 0.77 | PTGDR2 (0.53) | CAMKK2CAMKK1ALDH1A1PTGDR2DHODH | |
| SCHEMBL30730923 | 0.77 | PTGDR2 (0.53) | CAMKK2CAMKK1ALDH1A1PTGDR2DHODH | |
| SCHEMBL29029016 | 0.77 | FOLH1 (0.46) | CAMKK2CAMKK1ALDH1A1GAAPTGDR2 | |
| SCHEMBL21565051 | 0.77 | PTGS2 (0.43) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32581-E | Certain substituted phenyl esters of nicotinic acid, compositions and methods of using same for treatment of hyperlipidemia | MERZ + CO. GMBH & CO. (DE) | 1988-01-19 | — | — | US | claimed |
| US-4321268-A | Certain substituted phenyl esters of nicotinic acid, compositions and methods of using same | MERZ & CO. (DE) | 1982-03-23 | — | — | US | claimed |